Semiglutide is  not just for weight loss. It can be used in microdosing which helps with mood, inflammation, and improved brain function. At higher doses it does help with weight loss. This is 1 peptide.

Semaglutide with B12 is an injectable or oral medication that may help regulate blood sugar, reduce appetite, and support weight management by activating the GLP-1 (glucagon-like peptide-1) receptor. This activation may enhance insulin release, lower glucagon levels, slow stomach emptying, and promote feelings of fullness. The injectable requires weekly check in. Oral treatment requires check in the initial week starting and week 3 of dose change. The dose is slowly increased. This medication is typically a long term therapy and not covered by insurance.

Semaglutide?

  • Semaglutide is a GLP-1 receptor agonist. It mimics a hormone called glucagon-like peptide-1 (GLP-1), which helps regulate appetite and blood sugar levels.
  • It’s sold under brand names like Ozempic (for diabetes) and Wegovy (for weight loss).

How does Semaglutide help with weight loss?

  • It reduces appetite and makes you feel full faster.
  • It slows gastric emptying, meaning food stays in the stomach longer, helping control hunger.
  • Studies show it can lead to significant weight loss when combined with diet and exercise.

Effectiveness

  • Clinical trials showed people using semaglutide lost on average about 15% of their body weight over 68 weeks.
  • This is more than most other weight loss medications on the market.

How is it used?

  • For weight loss, it’s usually given as a once-weekly injection.
  • Doses start low and are gradually increased to reduce side effects.

Side effects

  • Common: nausea, vomiting, diarrhea, constipation.
  • Usually mild to moderate and improve over time.
  • Rare but serious risks include pancreatitis or gallbladder issues.